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Model Repository

Period: 
Oct 31 2014

The Model Repository from the Drug Disease Model Resources (DDMoRe) consortium provides a home to a collection of computational models of disease and drug action that have been used in pharmaceutical and/or academic research. This publically available open-access resource will make it easier for researchers to share and reuse a variety of models developed to describe drug action, disease progression and more.

The Repository currently showcases a range of 'proof of concept' models describing drugs and diseases. Over time, DDMoRe will make available safety models and new models in key therapeutic areas including diabetes, oncology, CNS and infectious diseases.

Features

  • hosting of public and private models
  • recording of full model history
  • sharing of private models
  • indexed and searchable content

Downloadable files

  • PharmML model code (extension xml)
  • MDL model code (extension mdl)
  • NMTRAN model code (extension mod)
  • Data (extension csv or txt)
  • Implementation information (extension txt)

The DDMoRe Model Repository is compatible with and built on the Pharmacometrics Markup Language (PharmML), and supports the current Modelling Description Language (MDL). Models encoded in other formats can be submitted to the Repository, but the PharmML representation is required in order to benefit from the full set of features of the software.

Next releases

Upcoming versions of the DDMoRe Repository will feature

  • a smarter search engine based on metadata.
  • faceted browsing based on the types of available models
  • integration with the DDMoRe Interoperability Framework
  • a model qualification procedure

User feedback

As we are planning to continously improve on the Model Repository features and performance your feedback as a user is needed. Please provide your feedback using the DDMoRe forum.
 

Work package: 

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What's next?

What will happen next in the DDMoRe project plan?