Current Use and Developments Needed for Optimal Design in Pharmacometrics: A Study Performed Among DDMoRe’s European Federation of Pharmaceutical Industries and Associations Members. F Mentré, M Chenel, E Comets, J Grevel, A Hooker, MO Karlsson, M Lavielle and I Gueorguieva. CPT: Pharmacometrics... Read more
White Paper: Landscape on Technical and Conceptual Requirements and Competence Framework in Drug/Disease Modeling and Simulation.
G Vlasakakis, E Comets, A Keunecke, I Gueorguieva, P Magni, N Terranova, O Della Pasqua, E C de Lange and C Kloft. CPT: Pharmacometrics & Systems Pharmacology 2013... Read more
Second issue of the DDMoRe newsletter, an update on the second-year achievements of the DDMoRe project
Posted on 20 March 2013 | Filed under:
Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug development. L. Harnisch, I. Matthews, J. Chard and M.O. Karlsson on behalf of the DDMoRe consortium Partners and Contributors. CPT: Pharmacometrics & Systems Pharmacology, 2013, 2, e34... Read more
Posted on 12 March 2013 | Filed under: WP1
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth after administration of an anti-angiogenic agent, bevacizumab, as single-agent and combination therapy in tumor xenografts.
Maurizio Rocchetti, Massimiliano Germani, Francesca Del Bene, Italo Poggesi, Paolo Magni, Enrico Pesenti... Read more
Posted on 18 January 2013 | Filed under:
University College London (UCL) has become the 26th partner of DDMoRe.
For this partner, Bernard de Bono and Pierre Grenon will mainly participate in developing standards and ontologies for the DDMoRe project.
Posted on 14 November 2012 | Filed under: WP1
Target-mediated disposition model describing the dynamics of IL12 and IFNy after administration of a Mifepristone-inducible adenoviral vecor for IL-12 expression in mice.
Zinnia Patricia Parra-Guillen, Alvaro Janda, Pilar Alzuguren, Pedro Berraondo, Ruben Hernandez-Alcoceba and Inaki F. Troconiz.... Read more
Posted on 05 August 2012 | Filed under: WP1
A minimal model of tumor growth inhibition in combination regimens under the hypothesis of no interaction between drugs.
Paolo Magni, Nadia Terranova, Franscesca Del Bene, Massimiliano Germani and Giuseppe De Nicolao. IEEE Trans Biomed Eng. 2012, 59: 2161
One important issue in the... Read more
First issue DDMoRe newsletter, an update on the first-year achievements of the DDMoRe project
Posted on 14 February 2012 | Filed under: WP4
ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information.
Bernard de Bono, Pierre Grenon and Stephen John Sammut. Hum. Mutat. 2012, 33: 837
A significant proportion of biomedical resources carries information that cross references to... Read more